Sunday, May 22, 2011

Topinmate




Topinmate may be available in the countries listed below.


Ingredient matches for Topinmate



Topiramate

Topiramate is reported as an ingredient of Topinmate in the following countries:


  • Taiwan

International Drug Name Search

Friday, May 20, 2011

Diclofenac All Pro




Diclofenac All Pro may be available in the countries listed below.


Ingredient matches for Diclofenac All Pro



Diclofenac

Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Diclofenac All Pro in the following countries:


  • Argentina

International Drug Name Search

Thursday, May 19, 2011

Olexa




Olexa may be available in the countries listed below.


Ingredient matches for Olexa



Olanzapine

Olanzapine is reported as an ingredient of Olexa in the following countries:


  • Georgia

  • India

International Drug Name Search

Tuesday, May 17, 2011

Onglyza


Onglyza is a brand name of saxagliptin, approved by the FDA in the following formulation(s):


ONGLYZA (saxagliptin hydrochloride - tablet; oral)



  • Manufacturer: BRISTOL MYERS SQUIBB

    Approval date: July 31, 2009

    Strength(s): EQ 2.5MG BASE, EQ 5MG BASE [RLD]

Has a generic version of Onglyza been approved?


No. There is currently no therapeutically equivalent version of Onglyza available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Onglyza. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
    Patent 6,395,767
    Issued: May 28, 2002
    Inventor(s): Jeffrey A.; Robl & Richard B.; Sulsky & David J.; Augeri & David R.; Magnin & Lawrence G.; Hamann & David A.; Betebenner
    Assignee(s): Bristol-Myers Squibb Company
    Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula where x is 0 or 1 and y is 0 or 1 (provided that x=1 when y=0 and x=0 when y=1); n is 0 or 1; X is H or CN; and wherein R1, R2, R3 and R4 are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, and other diseases as set out herein, employing such DP 4 inhibitor *or a combination of such DP 4 inhibitor and one or more of another antidiabetic agent such as metformin, glyburide, troglitazone, pioglitazone, rosiglitazone and/or insulin and/or one or more of a hypolipidemic agent and/or anti-obesity agent and/or other therapeutic agent.
    Patent expiration dates:

    • February 16, 2021
      ✓ 
      Patent use: METHOD FOR TREATING TYPE II DIABETES BY ADMINISTERING SAXAGLIPTIN
      ✓ 
      Drug substance
      ✓ 
      Drug product




  • Coated tablet formulation and method
    Patent 7,951,400
    Issued: May 31, 2011
    Inventor(s): Desai; Divyakant S. & Li; Bing V.
    Assignee(s): Bristol-Myers Squibb Company
    A coated tablet formulation is provided which includes a medicament such as the DPP4-inhibitor, saxaglipitin or its HCl salt, which is subject to intra-molecular cyclization, which formulation includes a tablet core containing one or more fillers, and other conventional excipients, which tablet core includes a coating thereon which may include two or more layers, at least one layer of which is an inner seal coat layer which is formed of one or more coating polymers, a second layer of which is formed of medicament which is the DPP4-inhibitor and one or more coating polymers, and an optional, but preferable third outer protective layer which is formed of one or more coating polymers. A method for forming the coated tablet is also provided.
    Patent expiration dates:

    • November 30, 2028
      ✓ 
      Drug product



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • December 16, 2013 - CHANGES ARE BASED ON RESULTS FROM STUDY CV181057

    • July 31, 2014 - NEW CHEMICAL ENTITY

See also...

  • Onglyza Consumer Information (Drugs.com)
  • Onglyza Consumer Information (Wolters Kluwer)
  • Onglyza Consumer Information (Cerner Multum)
  • Onglyza Advanced Consumer Information (Micromedex)
  • Saxagliptin Consumer Information (Wolters Kluwer)
  • Saxagliptin Consumer Information (Cerner Multum)
  • Saxagliptin Advanced Consumer Information (Micromedex)

Friday, May 13, 2011

Propylthiouracil PCH




Propylthiouracil PCH may be available in the countries listed below.


Ingredient matches for Propylthiouracil PCH



Propylthiouracil

Propylthiouracil is reported as an ingredient of Propylthiouracil PCH in the following countries:


  • Netherlands

International Drug Name Search

Thursday, May 12, 2011

Onxol


Generic Name: paclitaxel (PAK li TAK sel)

Brand Names: Onxol, Taxol


What is Onxol (paclitaxel)?

Paclitaxel is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body.


Paclitaxel is used to treat breast cancer, lung cancer, and ovarian cancer. It is also used to treat AIDS-related Kaposi's sarcoma.


Paclitaxel may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Onxol (paclitaxel)?


Do not use this medication without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. You should not be given this medication if you are allergic to paclitaxel, or to other medications that contain an ingredient called Cremophor EL (polyoxyethylated castor oil). This includes cyclosporine (Gengraf, Neoral, Sandimmune) and teniposide (Vumon).

Before you receive paclitaxel, tell your doctor if you have liver disease, heart disease, or a severely weak immune system.


Paclitaxel can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Do not miss any scheduled appointments.


There are many other medicines that can interact with paclitaxel. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What should I discuss with my healthcare provider before receiving Onxol (paclitaxel)?


You should not be given this medication if you are allergic to paclitaxel, or to other medications that contain an ingredient called Cremophor EL (polyoxyethylated castor oil). This includes cyclosporine (Gengraf, Neoral, Sandimmune) and teniposide (Vumon).

Before you receive paclitaxel, tell your doctor if you are allergic to any drugs, or if you have:


  • liver disease;


  • heart disease; or




  • a severely weak immune system.



If you have any of these conditions, you may need a dose adjustment or special tests to safely receive paclitaxel.


FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not receive paclitaxel without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. It is not known whether paclitaxel passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is paclitaxel given?


Paclitaxel is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take up to 24 hours to complete.


Paclitaxel is usually given every 3 weeks. Follow your doctor's instructions.


Before your injection, you may be given other medications to help prevent a serious allergic reaction to paclitaxel.


Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.

If any of this medication gets on your skin, wash the area with soap and warm water right away.


Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are receiving paclitaxel.

Your heart rate may also be monitored through electrocardiograph or ECG (sometimes called an EKG). This machine measures electrical activity of the heart.


Paclitaxel can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Do not miss any scheduled appointments.


What happens if I miss a dose?


Contact your doctor if you miss an appointment for your paclitaxel injection.


What happens if I overdose?


Seek emergency medical attention if you think you have received too much of this medicine.

Overdose symptoms may include numbness or tingling, fever, chills, mouth sores, unusual bleeding or weakness, or any signs of infection.


What should I avoid while using Onxol (paclitaxel)?


Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are being treated with paclitaxel.


Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.


Onxol (paclitaxel) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • slow heart rate;




  • seizure (black-out or convulsions);




  • pale skin, easy bruising or bleeding, unusual weakness;




  • fever, chills, body aches, flu symptoms;




  • white patches or sores inside your mouth or on your lips;




  • numbness, tingling, or burning pain in your hands or feet;




  • increased blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats); or




  • warmth or redness under your skin.



Less serious side effects may include:



  • pain, swelling, redness, or skin color changes where the medicine was injected;




  • joint or muscle pain;




  • mild nausea, vomiting, diarrhea; or




  • hair loss.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Onxol (paclitaxel)?


There are many other medicines that can interact with paclitaxel. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

More Onxol resources


  • Onxol Side Effects (in more detail)
  • Onxol Use in Pregnancy & Breastfeeding
  • Onxol Drug Interactions
  • Onxol Support Group
  • 0 Reviews for Onxol - Add your own review/rating


  • Onxol Prescribing Information (FDA)

  • Onxol MedFacts Consumer Leaflet (Wolters Kluwer)

  • Onxol Advanced Consumer (Micromedex) - Includes Dosage Information

  • Paclitaxel Prescribing Information (FDA)

  • Paclitaxel Professional Patient Advice (Wolters Kluwer)

  • Paclitaxel Monograph (AHFS DI)

  • Paclitaxel MedFacts Consumer Leaflet (Wolters Kluwer)

  • Taxol Prescribing Information (FDA)

  • Taxol Consumer Overview



Compare Onxol with other medications


  • Breast Cancer
  • Breast Cancer, Adjuvant
  • Breast Cancer, Metastatic
  • Kaposi's Sarcoma
  • Non-Small Cell Lung Cancer
  • Ovarian Cancer
  • Wilms' Tumor


Where can I get more information?


  • Your doctor or pharmacist can provide more information about paclitaxel.

See also: Onxol side effects (in more detail)


Sunday, May 8, 2011

Zideron




Zideron may be available in the countries listed below.


Ingredient matches for Zideron



Dextropropoxyphene

Dextropropoxyphene hydrochloride (a derivative of Dextropropoxyphene) is reported as an ingredient of Zideron in the following countries:


  • Greece

International Drug Name Search

Ondansetron Nycomed




Ondansetron Nycomed may be available in the countries listed below.


Ingredient matches for Ondansetron Nycomed



Ondansetron

Ondansetron hydrochloride (a derivative of Ondansetron) is reported as an ingredient of Ondansetron Nycomed in the following countries:


  • Norway

  • Switzerland

Ondansetron hydrochloride dihydrate (a derivative of Ondansetron) is reported as an ingredient of Ondansetron Nycomed in the following countries:


  • Denmark

  • Sweden

International Drug Name Search

Sevredol




Sevredol may be available in the countries listed below.


UK matches:

  • Sevredol tablets 10mg 20mg and 50mg
  • Sevredol tablets 10mg, 20mg and 50mg (SPC)

Ingredient matches for Sevredol



Morphine

Morphine is reported as an ingredient of Sevredol in the following countries:


  • Latvia

Morphine sulphate pentahydrate (a derivative of Morphine) is reported as an ingredient of Sevredol in the following countries:


  • Australia

  • Croatia (Hrvatska)

  • Czech Republic

  • Estonia

  • France

  • Germany

  • Hungary

  • Ireland

  • New Zealand

  • Poland

  • Portugal

  • Romania

  • Slovakia

  • Slovenia

  • Spain

  • Switzerland

  • United Kingdom

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Wednesday, May 4, 2011

Koleskol




Koleskol may be available in the countries listed below.


Ingredient matches for Koleskol



Pravastatin

Pravastatin sodium salt (a derivative of Pravastatin) is reported as an ingredient of Koleskol in the following countries:


  • Indonesia

International Drug Name Search

Sunday, May 1, 2011

Kaltide




Kaltide may be available in the countries listed below.


Ingredient matches for Kaltide



Amiloride

Amiloride hydrochloride dihydrate (a derivative of Amiloride) is reported as an ingredient of Kaltide in the following countries:


  • Bangladesh

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Kaltide in the following countries:


  • Bangladesh

International Drug Name Search

Ketoconazol A




Ketoconazol A may be available in the countries listed below.


Ingredient matches for Ketoconazol A



Ketoconazole

Ketoconazole is reported as an ingredient of Ketoconazol A in the following countries:


  • Netherlands

International Drug Name Search

Rispéridone Teva




Rispéridone Teva may be available in the countries listed below.


Ingredient matches for Rispéridone Teva



Risperidone

Risperidone is reported as an ingredient of Rispéridone Teva in the following countries:


  • France

International Drug Name Search