Epiduo Gel

Pronunciation: a-DAP-a-leen/BEN-zoe-il per-OX-ide
Generic Name: Adapalene and Benzoyl Peroxide
Brand Name: Epiduo

Epiduo Gel is used for:

Treating acne. It may also be used for other conditions as determined by your doctor.

Epiduo Gel is a combination of a retinoid and a keratolytic agent with antibacterial activity. Exactly how Epiduo Gel works to treat acne is not known. It helps to decrease acne formation by causing skin peeling and killing bacteria that cause acne.

Do NOT use Epiduo Gel if:

• you are allergic to any ingredient in Epiduo Gel

Contact your doctor or health care provider right away if any of these apply to you.

Before using Epiduo Gel:

Some medical conditions may interact with Epiduo Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have eczema, damaged skin, or a sunburn at the affected area


• if you have a history of skin sensitivity to the sun, or if you spend a lot of time outdoors


• if you are using other medicine to treat acne, especially medicines containing sulfur, resorcinol, or salicylic acid

Some MEDICINES MAY INTERACT with Epiduo Gel. Because little, if any, of Epiduo Gel is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Epiduo Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Epiduo Gel:

Use Epiduo Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Epiduo Gel. Talk to your pharmacist if you have questions about this information.


• Do not apply Epiduo Gel to eczema or to damaged or sunburned skin.


• Before applying Epiduo Gel, clean the area to be treated with mild soap or soapless cleanser and gently dry.


• Apply a thin film of Epiduo Gel to the affected skin and the surrounding area. Use a pea-sized amount for each area of the face (eg, forehead, chin, cheek) unless your doctor tells you otherwise. Rub in gently.


• Wash your hands right away after using Epiduo Gel.


• A mild sensation of warmth or slight stinging may occur shortly after using Epiduo Gel.


• If you miss a dose of Epiduo Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. If several applications are missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Epiduo Gel.

Important safety information:

• Epiduo Gel is for external use only. Do not get it in your eyes, mouth, nose, or in the angles of your nose. Do not get it in your vagina. If you get it in any of these areas, rinse right away with cool water.


• Do not use more than the recommended dose or more often than 1 time daily without checking with your doctor. This will not produce faster results and may increase irritation.


• Acne may worsen in the early stages of using Epiduo Gel. This is due to the action of Epiduo Gel on unseen lesions. Check with your doctor if your symptoms do not improve after several weeks.


• Do not use other medicines or products on your skin while you are using Epiduo Gel without first checking with your doctor.


• Do not use irritating products on the affected skin while you are using Epiduo Gel. These products may include abrasive soaps and cleansers, soaps and cosmetics with strong skin-drying effects, and products with high amounts of alcohol, astringents, spices, or limes.


• Cosmetics may be used while you are using Epiduo Gel. After using cosmetics, wash and dry the affected area well before you apply Epiduo Gel.


• Epiduo Gel may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Epiduo Gel. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Wind or cold temperatures may irritate the affected area while you are using Epiduo Gel.


• Mild redness, scaling, dryness, stinging, or burning may occur when you start Epiduo Gel. These effects usually decrease with continued use of Epiduo Gel. Talk with your doctor if these effects continue or become bothersome.


• Skin moisturizers may be used if necessary. Do not use moisturizers that contain alpha hydroxy or glycolic acids.


• Certain cosmetic procedures, such as waxing, should not be performed on treated skin due to possible irritation.


• Epiduo Gel may bleach hair and colored fabrics.


• Epiduo Gel may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.


• Epiduo Gel should be used with extreme caution in CHILDREN younger than 12 years; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Epiduo Gel while you are pregnant. It is not known if Epiduo Gel is found in breast milk. If you are or will be breast-feeding while you use Epiduo Gel, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Epiduo Gel:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry skin; feeling of warmth; irritation; itching; peeling; redness; scaling; temporary burning and stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blistering; crusting; excessive redness, peeling, or irritation; swelling.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Epiduo side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Epiduo Gel may be harmful if swallowed.

Proper storage of Epiduo Gel:

Store Epiduo Gel at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store with cap tightly closed away from heat, moisture, and light. Keep Epiduo Gel out of the reach of children and away from pets.

General information:

• If you have any questions about Epiduo Gel, please talk with your doctor, pharmacist, or other health care provider.


• Epiduo Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Epiduo Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Epiduo resources

• Epiduo Side Effects (in more detail)
• Epiduo Use in Pregnancy & Breastfeeding
• Epiduo Drug Interactions
• Epiduo Support Group
• 26 Reviews for Epiduo - Add your own review/rating

Compare Epiduo with other medications

• Acne

Augmentin XR

Generic Name: amoxicillin and clavulanate (Oral route)

a-mox-i-SIL-in, KLAV-ue-la-nate poe-TAS-ee-um

Commonly used brand name(s)

In the U.S.

• Amoclan


• Augmentin


• Augmentin ES-600


• Augmentin XR

In Canada

• Alti-Amoxi Clav


• Apo-Amoxi Clav


• Novo-Clavamoxin 125


• Novo-Clavamoxin 250


• Ratio-Amoxi Clav 250f

Available Dosage Forms:

• Tablet


• Tablet, Extended Release


• Powder for Suspension


• Tablet, Chewable

Therapeutic Class: Antibiotic

Pharmacologic Class: Penicillin, Aminopenicillin

Uses For Augmentin XR

Amoxicillin and clavulanate combination is used to treat bacterial infections in many different parts of the body.

Amoxicillin and clavulanate combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Before Using Augmentin XR

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of amoxicillin and clavulanate chewable tablets and oral suspension in children.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of amoxicillin and clavulanate tablets in children weighing 40 kilograms (kg) or more. However, safety and efficacy have not been established in children weighing less than 40 kg.

Appropriate studies have not been performed on the relationship of age to the effects of amoxicillin and clavulanate extended-release tablets in teenagers and children younger than 16 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amoxicillin and clavulanate combination in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving amoxicillin and clavulanate combination.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Methotrexate


• Venlafaxine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol


• Desogestrel


• Dienogest


• Drospirenone


• Estradiol Cypionate


• Estradiol Valerate


• Ethinyl Estradiol


• Ethynodiol Diacetate


• Etonogestrel


• Khat


• Levonorgestrel


• Medroxyprogesterone Acetate


• Mestranol


• Norelgestromin


• Norethindrone


• Norgestimate


• Norgestrel


• Probenecid


• Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Diarrhea or


• Liver disease—Use with caution. May make these conditions worse.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

• Kidney disease, severe—The extended-release tablets should not be used in patients with this condition.

• Liver disease, history of with amoxicillin and clavulanate combination or


• Mononucleosis ("mono")—Should not be used in patients with these conditions.

• Phenylketonuria (PKU)—The chewable tablet and oral suspension contain phenylalanine, which can make this condition worse.

Proper Use of amoxicillin and clavulanate

This section provides information on the proper use of a number of products that contain amoxicillin and clavulanate. It may not be specific to Augmentin XR. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You may take this medicine with or without meals. However, it is best to take this medicine at the start of a meal or snack to avoid an upset stomach.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

If you are using the chewable tablets, chew the tablet completely before swallowing.

There are certain flavors that can be mixed with the oral suspension to make it taste better. If you or your child do not like the taste of this medicine, ask your pharmacist about these flavorings.

Keep the oral suspension refrigerated. Shake it well before measuring the dose. Use a dosing spoon or medicine dropper to measure the dose. The average household teaspoon may not hold the right amount of liquid. Rinse the dosing spoon or dropper with water after each use.

Do not change brands or dosage forms of amoxicillin and clavulanate combination without first checking with your doctor. Different products may not work the same way. If you refill your medicine and it looks different, ask your pharmacist about the change.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For bacterial infections:
  
  • For oral dosage form (chewable tablets, suspension):
    
    • Adults, teenagers, and children weighing 40 kilograms (kg) or more—250 to 500 milligrams (mg) every eight hours or 500 to 875 mg every twelve hours.
    
    
    • Children and infants above 3 months of age and weighing less than 40 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The usual dose is 20 to 40 milligrams (mg) per kilogram (kg) of body weight per day (mg/kg/day), divided and given every 8 hours, or 25 to 90 mg/kg/day, divided and given every 12 hours.
    
    
    • Infants younger than 3 months of age—Dose is based on body weight and must be determined by your doctor. The usual dose is 30 milligrams (mg) per kilogram (kg) of body weight per day, divided and given every 12 hours.
    
    
  
  
  • For oral dosage form (extended-release tablets):
    
    • Adults—2000 milligrams (mg) every 12 hours.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For oral dosage form (tablets):
    
    • Adults, teenagers, and children weighing 40 kilograms (kg) or more—250 to 500 milligrams (mg) every eight hours or 500 to 875 mg every twelve hours.
    
    
    • Children weighing less than 40 kilograms (kg)—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the chewable tablets, regular tablets, and extended-release tablets at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral suspension in the refrigerator. Throw away any unused portion after 10 days. Keep from freezing.

Precautions While Using Augmentin XR

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you or your child have itching; hives; hoarseness; shortness of breath; trouble with breathing; trouble with swallowing; or any swelling of your hands, face, or mouth after you receive this medicine.

Amoxicillin and clavulanate combination may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

In some young patients, tooth discoloration may occur while using this medicine. The teeth may appear to have brown, yellow, or gray stains. To help prevent this, brush and floss your teeth regularly or have a dentist clean your teeth.

Amoxicillin and clavulanate combination may decrease the effects of some oral contraceptives (birth control pills). To avoid an unwanted pregnancy, it is a good idea to use additional contraceptive measures with your pills (e.g., condoms, a diaphragm, or a contraceptive foam or jelly) while using this medicine.

Before you or your child have any medical tests, tell the doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Augmentin XR Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Hives or welts


• itching


• itching of the vagina or genital area


• pain during sexual intercourse


• redness of the skin


• skin rash


• thick, white vaginal discharge with no odor or with a mild odor

Rare

• Bloody or cloudy urine


• fever


• greatly decreased frequency of urination or amount of urine


• seizures


• swelling of the feet or lower legs

Incidence not known

• Abdominal or stomach cramps or tenderness


• back, leg, or stomach pains


• black, hairy tongue


• black, tarry stools


• bleeding gums


• blistering, peeling, or loosening of the skin


• bloating


• blood in the stools


• bloody nose


• chest pain


• chills


• clay-colored stools


• cough or hoarseness


• cracks in the skin


• dark urine


• diarrhea


• diarrhea, watery and severe, which may also be bloody


• difficulty with breathing


• difficulty with moving


• difficulty with swallowing


• dizziness


• fast heartbeat


• fever with or without chills


• general body swelling


• general feeling of tiredness or weakness


• headache


• heavier menstrual periods


• increased thirst


• joint or muscle pain


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• light-colored stools


• loss of appetite


• loss of heat from the body


• lower back or side pain


• muscle stiffness


• nausea or vomiting


• pain


• pain, swelling, or redness in the joints


• painful or difficult urination


• pale skin


• pinpoint red spots on the skin


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• rash


• red skin lesions, often with a purple center


• red, irritated eyes


• red, swollen skin


• scaly skin


• shortness of breath


• sore throat


• sores, ulcers, or white spots on the lips or in the mouth


• swollen glands


• tightness in the chest


• troubled breathing with exertion


• unpleasant breath odor


• unusual bleeding or bruising


• unusual tiredness or weakness


• unusual weight loss


• upper right abdominal pain


• vomiting of blood


• wheezing


• white patches in the mouth or throat or on the tongue


• white patches with diaper rash


• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Abdominal or stomach pain


• bloody or cloudy urine


• diarrhea


• fever


• greatly decreased frequency of urination or amount of urine


• pain or burning while urinating


• skin rash


• sleepiness


• swelling of the feet or lower legs


• vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

• Anxiety


• dry mouth


• hyperventilation


• irregular heartbeats


• irritability


• nervousness


• restlessness


• shaking


• sleeplessness


• tooth discoloration


• trouble sitting still


• trouble with sleeping


• unable to sleep

Incidence not known

• Burning feeling in the chest or stomach


• indigestion


• redness, swelling, or soreness of the tongue


• stomach upset


• swelling or inflammation of the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Augmentin XR side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Augmentin XR resources

• Augmentin XR Side Effects (in more detail)
• Augmentin XR Use in Pregnancy & Breastfeeding
• Drug Images
• Augmentin XR Drug Interactions
• Augmentin XR Support Group
• 2 Reviews for Augmentin XR - Add your own review/rating

• Augmentin XR Prescribing Information (FDA)


• Augmentin XR Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Augmentin MedFacts Consumer Leaflet (Wolters Kluwer)


• Augmentin Prescribing Information (FDA)


• Augmentin Consumer Overview


• Augmentin ES-600 Prescribing Information (FDA)


• Augmentin ES-600 Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Augmentin XR with other medications

• Aspiration Pneumonia
• Bacterial Infection
• Bronchitis
• Febrile Neutropenia
• Kidney Infections
• Melioidosis
• Otitis Media
• Pneumonia
• Sinusitis
• Skin and Structure Infection
• Skin Infection
• Small Bowel Bacterial Overgrowth
• Strep Throat
• Upper Respiratory Tract Infection
• Urinary Tract Infection

Ssd Topical

Generic Name: silver sulfadiazine (Topical route)

SIL-ver sul-fa-DYE-a-zeen

Commonly used brand name(s)

In the U.S.

• Silvadene


• SSD


• SSD AF


• Thermazene

In Canada

• Flamazine


• Ssd

Available Dosage Forms:

• Cream

Therapeutic Class: Antibacterial

Chemical Class: Sulfonamide

Uses For Ssd

Silver sulfadiazine , a sulfa medicine, is used to prevent and treat bacterial or fungus infections. It works by killing the fungus or bacteria.

Silver sulfadiazine cream is applied to the skin and/or burned area(s) to prevent and treat bacterial or fungus infections that may occur in burns. This medicine may also be used for other problems as determined by your doctor.

Other medicines are used along with this medicine for burns. Patients with severe burns or burns over a large area of the body must be treated in a hospital.

Silver sulfadiazine is available only with your doctor's prescription.

Before Using Ssd

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Use is not recommended in premature or newborn infants up to 2 months of age. Sulfa medicines may cause liver problems in these infants. Although there is no specific information comparing use of silver sulfadiazine in older infants and children with use in other age groups, this medicine is not expected to cause different side effects or problems in older infants and children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of silver sulfadiazine in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood problems or


• Glucose-6-phosphate dehydrogenase deficiency (lack of G6PD enzyme)—Use of this medicine may cause blood problems or make them worse

• Kidney disease or


• Liver disease—In persons with these conditions, use may result in higher blood levels of this medicine; a smaller dose may be needed

• Porphyria—Use of this medicine may result in a severe attack of porphyria

Proper Use of silver sulfadiazine

This section provides information on the proper use of a number of products that contain silver sulfadiazine. It may not be specific to Ssd. Please read with care.

This medicine should not be used on premature or newborn infants up to 2 months of age, unless otherwise directed by your doctor. It may cause liver problems in these infants.

To use:

• Before applying this medicine, cleanse the affected area(s). Remove dead or burned skin and other debris.


• Wear a sterile glove to apply this medicine. Apply a thin layer (about 1/16 inch) of silver sulfadiazine to the affected area(s). Keep the affected area(s) covered with the medicine at all times.


• If this medicine is rubbed off the affected area(s) by moving around or if it is washed off during bathing, showering, or the use of a whirlpool bath, reapply the medicine.


• After this medicine has been applied, the treated area(s) may be covered with a dressing or left uncovered as desired.

To help clear up your skin and/or burn infection completely, keep using silver sulfadiazine for the full time of treatment. You should keep using this medicine until the burned area has healed or is ready for skin grafting. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage form (cream):
  
  • For burn wound infections:
    
    • Adults and children 2 months of age and older—Use one or two times a day.
    
    
    • Premature and newborn infants up to 2 months of age—Use and dose must be determined by the doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Ssd

It is important that your doctor check your progress at regular visits.

If your skin infection or burn does not improve within a few days or weeks (for more serious burns or burns over larger areas), or if it becomes worse, check with your doctor.

This medicine may rarely stain skin brownish gray.

Ssd Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

• Blistering, peeling or loosening of skin


• bloody or cloudy urine


• chills or fever


• cough


• decreased amount of urine or less frequent urination


• increased sensitivity of skin to sunlight, especially in patients with burns on large areas


• intense itching of burn wounds


• pain at site of application


• painful or difficult urination


• red skin lesions, often with a purple center


• shortness of breath


• sore throat


• sores, ulcers or white spots on lips or in mouth


• swollen glands


• unusual bleeding or bruising


• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Burning feeling on treated area(s)

Less common or rare

• Brownish-gray skin discoloration


• itching or skin rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Ssd Topical side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Ssd Topical resources

• Ssd Topical Side Effects (in more detail)
• Ssd Topical Use in Pregnancy & Breastfeeding
• Ssd Topical Drug Interactions
• 0 Reviews for Ssd Topical - Add your own review/rating

Compare Ssd Topical with other medications

• Burns, External

Atrovent Inhalation, oral/nebulization

Generic Name: ipratropium (Inhalation route)

ip-ra-TROE-pee-um BROE-mide

Commonly used brand name(s)

In the U.S.

• Atrovent

In Canada

• Alti-Ipratropium


• Alti-Ipratropium With Preservative


• Apo-Ipravent


• Ipratropium Bromide Nebuamp


• Ipratrovent Sterules


• Ratio-Ipratropium


• Ratio-Ipratropium Udv

Available Dosage Forms:

• Solution


• Aerosol Powder

Therapeutic Class: Bronchodilator

Pharmacologic Class: Ipratropium

Uses For Atrovent

Ipratropium is used to help control the symptoms of lung diseases, such as asthma, chronic bronchitis, and emphysema. It is also used to treat air flow blockage and prevent the worsening of chronic obstructive pulmonary disease (COPD).

Ipratropium belongs to the family of medicines known as bronchodilators. Bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs.

This medicine is available only with your doctor's prescription.

Before Using Atrovent

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of ipratropium in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ipratropium in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Betel Nut

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to atropine, scopolamine, or hyoscyamine—Should not be used in patients with this condition.

• Difficult urination or


• Enlarged prostate or


• Narrow-angle glaucoma or


• Urinary bladder blockage—Use with caution. May make these conditions worse.

Proper Use of ipratropium

This section provides information on the proper use of a number of products that contain ipratropium. It may not be specific to Atrovent. Please read with care.

This medicine usually comes with patient instructions. Read them carefully before using the medicine. If you do not understand the directions or you are not sure how to use the inhaler, ask your doctor to show you how to use it.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine without telling your doctor. To do so may cause your lung condition to become worse.

Keep the spray or solution away from the eyes. This medicine may cause eye pain or discomfort, irritation, blurred vision, or start seeing halos or odd colors when you look at things. Closing your eyes while you are inhaling ipratropium may keep the medicine from getting into your eyes. If it does come into contact with your eyes, check with your doctor right away.

If you are taking this medicine every day to help control your symptoms, it must be taken at regularly spaced times as ordered by your doctor.

For patients using ipratropium inhalation aerosol:

• If you do not understand the directions or you are not sure how to use the inhaler, ask your doctor to show you how to use it. Also, ask your doctor to check regularly how you use the inhaler to make sure you are using it properly.


• There are two formulas of the inhaled aerosol. One contains chlorofluorocarbons and the other contains HFA as the propellant. The taste and inhalation of these may seem different, but the safety and effectiveness of both formulas are similar.


• The ipratropium aerosol canister provides about 200 inhalations, depending on the size of the canister your doctor ordered. You should try to keep a record of the number of inhalations you use so you will know when the canister is almost empty. This canister, unlike some other aerosol canisters, cannot be floated in water to test its fullness.


• When you use the inhaler for the first time, or if you have not used it for a while, the inhaler may not give the right amount of medicine with the first puff. Therefore, before using the inhaler, test or prime it.


• To test or prime the inhaler:
  
  • Insert the canister firmly into the clean mouthpiece according to the manufacturer's instructions. Check to make sure it is placed properly into the mouthpiece.
  
  
  • Take the cap off the mouthpiece and shake the inhaler three or four times.
  
  
  • Hold the inhaler away from you at arm's length and press the top of the canister, spraying the medicine two times into the air. The inhaler will now be ready to give the right amount of medicine when you use it.
  
  
  • If the inhaler is not used for more than 3 days, prime the inhaler two times to prepare it for use.
  
  


• To use the inhaler:
  
  • Using your thumb and one or two fingers, hold the inhaler upright, with the mouthpiece end down and pointing toward you.
  
  
  • Take the cap off the mouthpiece. Check the mouthpiece to make sure it is clear. Then, gently shake the inhaler three or four times.
  
  
  • Breathe out slowly to the end of a normal breath.
  
  
  • Use the inhalation method recommended by your doctor:
    
    • Open-mouth method—Place the mouthpiece about 1 or 2 inches (2 finger-widths) in front of your widely opened mouth. Make sure the inhaler is aimed into your mouth so the spray does not hit the roof of your mouth or your tongue.
    
    
    • Closed-mouth method—Place the mouthpiece in your mouth between your teeth and over your tongue with your lips closed tightly around it. Make sure your tongue or teeth are not blocking the opening.
    
    
  
  
  • Start to breathe in slowly and deeply through your mouth. At the same time, press the top of the canister once to get one puff of medicine. Continue to breathe in slowly for 5 to 10 seconds. Count the seconds while breathing in. It is important to press the canister and breathe in slowly at the same time so the medicine gets into your lungs. This step may be difficult at first. If you are using the closed-mouth method and you see a fine mist coming from your mouth or nose, the inhaler is not being used correctly.
  
  
  • Hold your breath as long as you can up to 10 seconds. This gives the medicine time to settle into your airways and lungs.
  
  
  • Take the mouthpiece away from your mouth and breathe out slowly.
  
  
  • If your doctor has told you to inhale more than one puff of medicine at each dose, gently shake the inhaler again, and take the second puff following exactly the same steps you used for the first puff. Press the canister one time for each puff of medicine.
  
  
  • When you are finished, wipe off the mouthpiece and replace the cap.
  
  


• Your doctor may want you to use a spacer device or holding chamber with the inhaler. A spacer helps get the medicine into the lungs and reduces the amount of medicine that stays in your mouth and throat.
  
  • To use a spacer device with the inhaler:
    
    • Attach the spacer to the inhaler according to the manufacturer's directions. There are different types of spacers available, but the method of breathing remains the same with most spacers.
    
    
    • Gently shake the inhaler and spacer three or four times.
    
    
    • Hold the mouthpiece of the spacer away from your mouth and breathe out slowly to the end of a normal breath.
    
    
    • Place the mouthpiece into your mouth between your teeth and over your tongue with your lips closed around it.
    
    
    • Press the top of the canister once to release one puff of medicine into the spacer. Within 1 or 2 seconds, start to breathe in slowly and deeply through your mouth for 5 to 10 seconds. Count the seconds while inhaling. Do not breathe in through your nose.
    
    
    • Hold your breath as long as you can up to 10 seconds.
    
    
    • Take the mouthpiece away from your mouth and breathe out slowly.
    
    
    • If your doctor has told you to take more than one puff of medicine at each dose, gently shake the inhaler and spacer again and take the next puff, following exactly the same steps you used for the first puff. Do not put more than one puff of medicine into the spacer at a time.
    
    
    • When you are finished, remove the spacer device from the inhaler and replace the cap.
    
    
  
  


• The mouthpiece has a dose indicator window that shows how much medicine is left. When the dose indicator window displays "40" or changes from green to red color background, this means that you need to refill your prescription or ask your doctor if you need another prescription of this medicine.


• Clean the inhaler, mouthpiece, and spacer at least once a week.
  
  • To clean the inhaler:
    
    • Remove the canister from the inhaler and set aside.
    
    
    • Wash the mouthpiece, cap, and the spacer with warm, soapy water. Then, rinse well with warm, running water.
    
    
    • Shake off the excess water and let the inhaler parts air dry completely before putting the inhaler back together.
    
    
  
  

For patients using the inhalation solution:

• Use this medicine only in a power-operated nebulizer with an adequate flow rate and equipped with a face mask or mouthpiece. Your doctor will tell you which nebulizer to use. Make sure you understand exactly how to use it. If you have any questions about this, check with your doctor.


• To prepare the medicine for use in the nebulizer:
  
  • If you are using the single-dose vial of ipratropium:
    
    • Break away one vial by pulling it firmly from the strip.
    
    
    • Twist off the top to open the vial. Use the contents of the vial as soon as possible after opening it.
    
    
    • Squeeze the contents of the vial into the cup of the nebulizer. If your doctor has told you to use less than a full vial of solution, use a syringe to withdraw the correct amount of solution from the vial and add it to the nebulizer cup. Be sure to throw away the syringe after one use.
    
    
  
  
  • If you are using the multiple-dose bottle of ipratropium:
    
    • Use a syringe to withdraw the correct amount of solution from the bottle and add it to the nebulizer cup. Do not use the same syringe more than once.
    
    
  
  


• If you have been told to dilute the ipratropium inhalation solution in the nebulizer cup with the sodium chloride solution provided, use a new syringe to add the sodium chloride solution to the cup as directed by your doctor.


• If your doctor told you to use another inhalation solution with the ipratropium inhalation solution, add that solution also to the nebulizer cup.


• To use the nebulizer:
  
  • Gently shake the nebulizer cup to mix the solutions well.
  
  
  • Connect the nebulizer tube to the air or oxygen pump and begin the treatment. Adjust the mask, if you are using one, to prevent mist from getting into your eyes.
  
  
  • Use the method of breathing your doctor told you to use to take the treatment. One way is to breathe slowly and deeply through the mask or mouthpiece. Another way is to breathe in and out normally with the mouthpiece in your mouth, taking a deep breath every 1 or 2 minutes. Continue to breathe in the medicine as instructed until no more mist is formed in the nebulizer cup or until you hear a sputtering (spitting or popping) sound.
  
  
  • When you have finished, replace the caps on the solutions. Store the bottles of solution in the refrigerator until the next treatment.
  
  
  • Clean the nebulizer according to the manufacturer's directions.
  
  

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For asthma:
  
  • For inhalation aerosol dosage form (used with an inhaler):
    
    • Adults and children 12 years of age and older—1 to 4 puffs four times a day, at regularly spaced times, as needed.
    
    
    • Children up to 12 years of age—1 or 2 puffs three or four times a day, at regularly spaced times, as needed.
    
    
  
  
  • For inhalation solution dosage form (used with a nebulizer):
    
    • Adults and children 12 years of age and older—500 mcg used in a nebulizer three or four times a day, every 6 to 8 hours, as needed.
    
    
    • Children 5 to 12 years of age—125 to 250 mcg used in a nebulizer three or four times a day, every 4 to 6 hours as needed.
    
    
    • Children up to 5 years of age—Use and dose must be determined by your doctor.
    
    
  
  


• For symptoms of chronic obstructive pulmonary disease (COPD):
  
  • For inhalation aerosol dosage form (used with an inhaler):
    
    • Adult—At first, 2 puffs four times a day and as needed. Do not use more than 12 puffs in any 24-hour period.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For inhalation solution dosage form (used with a nebulizer):
    
    • Adults and children 12 years of age and older—250 to 500 mcg used in a nebulizer three or four times a day, every 6 to 8 hours.
    
    
    • Children up to 12 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Atrovent

It is very important that your doctor check your progress closely while you are using this medicine to see if it is working properly and to help reduce any unwanted effects.

Check with your doctor at once if your symptoms do not improve within 30 minutes after using a dose of this medicine or if your condition gets worse.

For patients using ipratropium inhalation solution:

• If you are also using cromolyn inhalation solution, do not mix that solution with the ipratropium inhalation solution containing the preservative benzalkonium chloride for use in a nebulizer. To do so will cause the solution to become cloudy. However, if your condition requires you to use cromolyn inhalation solution with ipratropium inhalation solution, it may be mixed with ipratropium inhalation solution that is preservative-free.

This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop using this medicine and call your doctor right away if you have a rash; itching; hives; hoarseness; trouble with breathing; trouble with swallowing; or any swelling of your hands, face, mouth, or throat while you are using this medicine.

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Stop using this medicine and check with your doctor right away if you have coughing, difficulty breathing, shortness of breath, or wheezing after using this medicine.

This medicine may cause dizziness, blurred vision, or trouble in seeing clearly. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert, well-coordinated, or able to see well.

Take all of your COPD medicines as your doctor ordered. If you use any type of corticosteroid medicine to control your breathing, keep using it as ordered by your doctor. This includes corticosteroid medicines that are taken by mouth or inhaled (such as prednisone, Azmacort®, or Flovent®). If any of your COPD medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.

Atrovent Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Bladder pain


• bloody or cloudy urine


• cough producing mucus


• difficult, burning, or painful urination


• difficulty with breathing


• frequent urge to urinate


• lower back or side pain


• shortness of breath


• tightness in the chest


• wheezing

Less common

• Body aches or pain


• chills


• cough


• ear congestion


• fever


• headache


• loss of voice


• runny nose


• sneezing


• sore throat


• unusual tiredness or weakness

Rare

• Constipation (continuing) or lower abdominal pain or bloating


• fainting


• fast, pounding, or irregular heartbeat or pulse


• severe eye pain


• skin rash or hives


• swelling of the face, lips, or eyelids

Incidence not known

• Blindness


• blurred vision


• confusion


• decrease in the frequency of urination


• decrease in the urine volume


• decreased vision


• difficulty in passing urine (dribbling)


• difficulty with swallowing


• dizziness


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• hives or welts


• itching


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• nausea or vomiting


• noisy breathing


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• redness of the skin


• redness of the white part of the eyes or inside of the eyelids


• sweating


• tearing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Back pain


• dryness of the mouth


• unpleasant taste

Less common or rare

• Acid or sour stomach


• belching


• burning eyes


• diarrhea


• general feeling of discomfort or illness


• heartburn


• indigestion


• joint pain


• loss of appetite


• muscle aches and pains


• nervousness


• pain or tenderness around the eyes and cheekbones


• shivering


• stomach discomfort, upset, or pain


• trembling


• trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Atrovent Inhalation,/nebulization side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Atrovent Inhalation, oral/nebulization resources

• Atrovent Inhalation, oral/nebulization Side Effects (in more detail)
• Atrovent Inhalation, oral/nebulization Use in Pregnancy & Breastfeeding
• Atrovent Inhalation, oral/nebulization Drug Interactions
• Atrovent Inhalation, oral/nebulization Support Group
• 3 Reviews for Atrovent Inhalation,/nebulization - Add your own review/rating

Compare Atrovent Inhalation, oral/nebulization with other medications

• Asthma
• COPD, Maintenance

Acriflex 0.25% w / w Chlorhexidine Gluconate Cream

1. Name Of The Medicinal Product

Acriflex (0.25% w/w Chlorhexidine Gluconate) Cream

2. Qualitative And Quantitative Composition

Acriflex (0.25% w/w Chlorhexidine Gluconate) Cream contains:

Chlorhexidine Gluconate 20% solution BP 1.25% v/w.

For excipients, see 6.1.

3. Pharmaceutical Form

Cream for topical administration to human beings.

4. Clinical Particulars

4.1 Therapeutic Indications

For the treatment of minor burns and scalds, scratches, cuts and abrasions, sunburn blisters and infected cracked skin.

4.2 Posology And Method Of Administration

For general use, apply freely and smooth gently into the skin. For cuts abrasions, burns etc. spread freely and, if necessary, cover with a dressing.

There are no recommended dosage schedules as the product is for use as needed.

4.3 Contraindications

Hypersensitivity to any of the ingredients.

4.4 Special Warnings And Precautions For Use

Keep away from the eyes.

Avoid contact with the brain, meninges and middle ear. Not for use in body cavities.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known.

4.6 Pregnancy And Lactation

No harmful effects in human pregnancy have been reported. Nevertheless, like all medicines, care should be exercised during pregnancy and lactation.

4.7 Effects On Ability To Drive And Use Machines

None known.

4.8 Undesirable Effects

Skin irritation may occur occasionally. Rarely, generalised allergic reactions to chlorhexidine have been reported.

4.9 Overdose

Overdosage is extremely unlikely. Chlorhexidine is poorly absorbed and systemic effects are unlikely even if large amounts are swallowed. However, gastric lavage followed by supportive measures may be used as appropriate.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Chlorhexidine is a bisbiguanide disinfectant which is effective against a wide range of vegetative gram-positive and gram-negative bacteria.

5.2 Pharmacokinetic Properties

Not applicable.

5.3 Preclinical Safety Data

Not applicable.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Arlatone 983 S

Cetostearyl Alcohol BP

Liquid Paraffin BP

Dimeticone 20 BPC

Glycerol BP

Quinoline Yellow Lake 250

Purified Water BP

6.2 Incompatibilities

None known.

6.3 Shelf Life

Three years unopened.

6.4 Special Precautions For Storage

None stated.

6.5 Nature And Contents Of Container

Internally lacquered aluminium, blind end tubes containing 25gm and 30gm of product, closed with a polyolefin cap in a cardboard outer.

6.6 Special Precautions For Disposal And Other Handling

None stated.

7. Marketing Authorisation Holder

Thornton & Ross Limited

Linthwaite

Huddersfield

West Yorkshire

HD7 5QH

United Kingdom

8. Marketing Authorisation Number(S)

PL 00240/0116

9. Date Of First Authorisation/Renewal Of The Authorisation

31 March 2003

10. Date Of Revision Of The Text

20^th October 2003

11 DOSIMETRY

Not Applicable

12 INSTRUCTIONS FOR PREPARATION OF RADIOPHARMACEUTICALS

Not Applicable

Multivitamins with Folic Acid/Iron/Docusate

Pronunciation: MUL-ti-VYE-ta-mins/FOE-lik AS-id/EYE-urn/DOK-ue-sate
Generic Name: Multivitamins with Folic Acid/Iron/Docusate
Brand Name: Examples include Nephron FA and Ferro-Plex Hematinic

Accidental overdose of products that contain iron is a leading cause of fatal poisoning in children younger than 6 years old. Keep this and all medicines out of the reach of children. In case of accidental ingestion, call a doctor or poison control center right away.

Multivitamins with Folic Acid/Iron/Docusate is used for:

Treating or preventing low levels of vitamins, folic acid, and iron in the body. It may also be used for other conditions as determined by your doctor.

Multivitamins with Folic Acid/Iron/Docusate is a vitamin, folic acid, iron, and stool softener combination. It works by providing extra vitamins, folic acid, and iron to the body when you need more than what you get in your diet. The stool softener helps prevent constipation that may occur with iron products.

Do NOT use Multivitamins with Folic Acid/Iron/Docusate if:

• you are allergic to any ingredient in Multivitamins with Folic Acid/Iron/Docusate


• you have certain iron metabolism problems (eg, hemosiderosis, hemochromatosis) or high levels of iron in your blood

Contact your doctor or health care provider right away if any of these apply to you.

Before using Multivitamins with Folic Acid/Iron/Docusate:

Some medical conditions may interact with Multivitamins with Folic Acid/Iron/Docusate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have bowel problems (eg, colitis, Crohn disease, diverticulitis), certain blood disorders (eg, hemolytic or pernicious anemia, porphyria cutanea tarda, thalassemia), glucose-6-phosphate-dehydrogenase (G6PD) deficiency, or a peptic ulcer


• if you have had multiple blood transfusions

Some MEDICINES MAY INTERACT with Multivitamins with Folic Acid/Iron/Docusate. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Fluorouracil because the risk of its side effects may be increased by Multivitamins with Folic Acid/Iron/Docusate


• Cephalosporin antibiotics (eg, cephalexin), eltrombopag, hydantoins (eg, phenytoin), methyldopa, mycophenolate, penicillamine, quinolone antibiotics (eg, ciprofloxacin), tetracycline antibiotics (eg, doxycycline), or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Multivitamins with Folic Acid/Iron/Docusate

This may not be a complete list of all interactions that may occur. Ask your health care provider if Multivitamins with Folic Acid/Iron/Docusate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Multivitamins with Folic Acid/Iron/Docusate:

Use Multivitamins with Folic Acid/Iron/Docusate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Multivitamins with Folic Acid/Iron/Docusate by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Take Multivitamins with Folic Acid/Iron/Docusate with a full glass of water (8 oz/240 mL).


• Do not take an antacid within 1 hour before or 2 hours after you take Multivitamins with Folic Acid/Iron/Docusate.


• Avoid taking Multivitamins with Folic Acid/Iron/Docusate with dairy products; they may interfere with the absorption of the iron in Multivitamins with Folic Acid/Iron/Docusate.


• If you miss a dose of Multivitamins with Folic Acid/Iron/Docusate, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Multivitamins with Folic Acid/Iron/Docusate.

Important safety information:

• Do not take large doses of vitamins while you use Multivitamins with Folic Acid/Iron/Docusate unless your doctor tells you to.


• Multivitamins with Folic Acid/Iron/Docusate may discolor the stools. This is normal and not a cause for concern.


• Multivitamins with Folic Acid/Iron/Docusate has iron in it. Iron overdose is a leading cause of fatal poisoning in children younger than 6 years old. In case of an overdose, call a doctor or poison control center right away.


• Multivitamins with Folic Acid/Iron/Docusate has pyridoxine (vitamin B₆), folic acid, and iron in it. Before you start any medicine, check the label to see if it has pyridoxine (vitamin B₆), folic acid, or iron in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Multivitamins with Folic Acid/Iron/Docusate while you are pregnant. It is not known if Multivitamins with Folic Acid/Iron/Docusate is found in breast milk. If you are or will be breast-feeding while you use Multivitamins with Folic Acid/Iron/Docusate, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Multivitamins with Folic Acid/Iron/Docusate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dark or discolored stools; diarrhea; nausea; stomach upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in the vomit; persistent nausea, vomiting, or diarrhea; stomach pain or cramping.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include black, tarry stools; blood in the vomit; diarrhea; headache; nausea; vomiting.

Proper storage of Multivitamins with Folic Acid/Iron/Docusate:

Store Multivitamins with Folic Acid/Iron/Docusate at room temperature. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Multivitamins with Folic Acid/Iron/Docusate out of the reach of children and away from pets.

General information:

• If you have any questions about Multivitamins with Folic Acid/Iron/Docusate, please talk with your doctor, pharmacist, or other health care provider.


• Multivitamins with Folic Acid/Iron/Docusate is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Multivitamins with Folic Acid/Iron/Docusate. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Multivitamins with Folic Acid/Iron/Docusate resources

• Multivitamins with Folic Acid/Iron/Docusate Use in Pregnancy & Breastfeeding
• Drug Images
• Multivitamins with Folic Acid/Iron/Docusate Drug Interactions
• Multivitamins with Folic Acid/Iron/Docusate Support Group
• 11 Reviews for Multivitamins with Folic Acid/Iron/Docusate - Add your own review/rating

Compare Multivitamins with Folic Acid/Iron/Docusate with other medications

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Niacin Controlled-Release Capsules

Pronunciation: NYE-uh-sin
Generic Name: Niacin
Brand Name: Slo-Niacin

Niacin Controlled-Release Capsules are used for:

Treating and preventing low levels of niacin. It may also be used for other conditions as determined by your doctor.

Niacin Controlled-Release Capsules are a water soluble B-complex vitamin. It works by supplementing your diet if you do not consume enough niacin from foods.

Do NOT use Niacin Controlled-Release Capsules if:

• you are allergic to any ingredient in Niacin Controlled-Release Capsules


• you are pregnant or breast-feeding or have gallbladder disease, gout, bleeding of the arteries, glaucoma, diabetes, liver problems, or a peptic ulcer, unless directed to by your doctor

Contact your doctor or health care provider right away if any of these apply to you.

Before using Niacin Controlled-Release Capsules:

Some medical conditions may interact with Niacin Controlled-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of bleeding problems, chest pain, diabetes, gallbladder problems, glaucoma, gout, heart problems or a recent heart attack, liver problems, low blood pressure, or stomach problems (eg, peptic ulcers)


• if you have an alcohol addiction


• if you are taking medicines that lower high blood pressure or cholesterol levels

Some MEDICINES MAY INTERACT with Niacin Controlled-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

• HMG-CoA reductase inhibitors ("statins") (eg, simvastatin) because side effects, such as muscle aches and weakness, may occur and may be a symptom of a serious medical condition called rhabdomyolysis


• Alcohol because toxic effects, such as delirium and lactic acidosis, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Niacin Controlled-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Niacin Controlled-Release Capsules:

Use Niacin Controlled-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Niacin Controlled-Release Capsules by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Swallow Niacin Controlled-Release Capsules whole. Do not break, crush, or chew before swallowing.


• If you miss a dose of Niacin Controlled-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Niacin Controlled-Release Capsules.

Important safety information:

• Niacin Controlled-Release Capsules may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Niacin Controlled-Release Capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Niacin Controlled-Release Capsules may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect. To prevent it, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of this effect.


• Niacin Controlled-Release Capsules may cause warmth or flushing. Check with your doctor for ways to lessen these effects.


• Do not use a different dosage form of Niacin Controlled-Release Capsules. Cases of severe liver toxicity, including fulminant hepatic necrosis, have occurred in patients who have substituted sustained-release (modified-release, timed-release) nicotinic acid products for immediate-release (crystalline) nicotinic acid at equivalent doses.


• Do not take large doses of vitamins while you use Niacin Controlled-Release Capsules unless your doctor tells you to.


• Diabetes patients - Niacin Controlled-Release Capsules may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Lab tests, including liver function tests and serum creatine kinase tests, may be performed while you use Niacin Controlled-Release Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Niacin Controlled-Release Capsules should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Niacin Controlled-Release Capsules while you are pregnant. It is not known if Niacin Controlled-Release Capsules are found in breast milk. If you are or will be breast-feeding while you use Niacin Controlled-Release Capsules, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Niacin Controlled-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Stomach upset; temporary skin redness, tingling or feelings of warmth (flushing).

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; changes in vision; cloudy or blurred vision; decrease in urine or dark-colored urine; fast or irregular heartbeat; flu-like symptoms (nausea, vomiting, "not well" feeling); loss of appetite; muscle weakness, swelling, tenderness, or pain; numbness or persistent tingling of the skin; swelling of the hands, legs, or feet; vomit that looks like coffee grounds; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Niacin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include flushing.

Proper storage of Niacin Controlled-Release Capsules:

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Niacin Controlled-Release Capsules out of the reach of children and away from pets.

General information:

• If you have any questions about Niacin Controlled-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.


• Niacin Controlled-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Niacin Controlled-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Niacin resources

• Niacin Side Effects (in more detail)
• Niacin Use in Pregnancy & Breastfeeding
• Niacin Drug Interactions
• Niacin Support Group
• 22 Reviews for Niacin - Add your own review/rating

Compare Niacin with other medications

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• Hyperlipoproteinemia
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• Hyperlipoproteinemia Type V, Elevated Chylomicrons VLDL
• Niacin Deficiency
• Pellagra