Generic Name: iloprost (ill O prost)
Brand Names: Ventavis
What is iloprost inhalation?
Iloprost is an synthetic prostacyclin. It works by opening blood vessels in the lungs.
Iloprost is used as an inhalant to treat pulmonary arterial hypertension.
Iloprost inhalation may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about iloprost inhalation?
Use iloprost inhalation exactly as directed by your doctor. Iloprost inhalation should only be used with the Prodose AAD system. Do not use iloprost inhalation with other types of nebulizers. If you do not understand your instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Iloprost inhalation may lower blood pressure which can lead to dizziness or fainting. Stand up slowly when getting out of a chair or bed. If you experience fainting or if your dizziness gets worse contact your doctor.
What should I discuss with my healthcare provider before taking iloprost inhalation?
Before taking this medication, tell your doctor if you have.
liver disease;
heart disease;
kidney disease;
low blood pressure;
chronic obstructive pulmonary disease (COPD);
asthma; or
a chest cold or cough.
You may need a lower dose or special monitoring during therapy with iloprost inhalation.
Iloprost is in the FDA pregnancy category C. This means that it is not known whether iloprost will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Iloprost passes into breast milk in small amounts and may affect a nursing baby. Do not take iloprost without first talking to your doctor if you are breast-feeding a baby.
How should I use iloprost inhalation?
Use iloprost inhalation exactly as directed by your doctor. Iloprost inhalation should only be used with the Prodose AAD system. Do not use it with other types of nebulizers. If you do not understand the instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Iloprost inhalation may cause a lowering of blood pressure which can lead to dizziness or fainting. Stand up slowly when getting out of a chair or bed. If you experience fainting or if your dizziness gets worse contact your doctor.
Store iloprost inhalation at room temperature away from moisture and heat.
What happens if I miss a dose?
Use the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and use the next one as directed. Do not use a double dose of this medication.
What happens if I overdose?
An overdose of this medication is not likely to occur. If you do suspect an overdose, call an emergency room or poison control center.
What should I avoid while taking iloprost inhalation?
Avoid items or activities that you know are allergens for you if they make your symptoms worse. Clean areas where dust or pet fur may aggravate your condition.
Do not stop taking iloprost inhalation until your doctor approves. It may be some time before you begin to notice effects from this medication.
Iloprost inhalation side effects
Serious side effects from iloprost inhalation are not likely to occur. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat, swelling of your lips, tongue, or face; or hives).
Other, less serious side effects may also occur. Continue to use iloprost inhalation and talk to your doctor if you experience
dry mouth, nose, or throat after use;
coughing or throat irritation;
hoarseness or deepening of the voice;
headache, dizziness, or lightheadedness;
nausea;
flushing; or
jaw tightness or pain.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Iloprost Dosing Information
Usual Adult Dose for Pulmonary Hypertension:
Iloprost is intended for inhalation administration via either of two pulmonary drug delivery devices: the Prodose AAD System or the I-neb AAD System. It has not been studied with any other nebulizers. The first inhaled dose should be 2.5 mcg. If this dose is well tolerated, dosing should be increased to 5 mcg and maintained at that dose. Iloprost should be taken 6 to 9 times per day (no more than every 2 hours) during walking hours, according to individual need and tolerability. The maximum daily dose evaluated in clinical studies was 45 mcg (5 mcg 9 times per day).
The 20 mcg/mL concentration is intended for patients who are maintained at the 5 mcg dose and who have repeatedly experienced extended treatment times which could result in incomplete dosing. Transitioning patients to the 20 mcg/mL concentration using the I-neb AAD System will decrease treatment times to help maintain patient compliance.
What other drugs will affect iloprost inhalation?
Before using this medication, tell your doctor and pharmacist about any other drugs you are taking including vitamins, minerals, and herbal products.
More iloprost resources
- Iloprost Side Effects (in more detail)
- Iloprost Dosage
- Iloprost Use in Pregnancy & Breastfeeding
- Iloprost Drug Interactions
- Iloprost Support Group
- 0 Reviews for Iloprost - Add your own review/rating
- iloprost Inhalation, oral/nebulization Advanced Consumer (Micromedex) - Includes Dosage Information
- Iloprost Professional Patient Advice (Wolters Kluwer)
- Iloprost MedFacts Consumer Leaflet (Wolters Kluwer)
- Iloprost Monograph (AHFS DI)
- Ventavis Prescribing Information (FDA)
- Ventavis Consumer Overview
Compare iloprost with other medications
- Pulmonary Arterial Hypertension
Where can I get more information?
- Your pharmacist has additional information about iloprost inhalation written for health professionals that you may read.
See also: iloprost side effects (in more detail)
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